A Course in Mathematical Biology William R. Derrick University of Montana Mathematical Biology is a fast growing, although not completely defined, area of mathematics that arose initially in the late 1920's with the work of Lotka and Volterra in population models and Kermack and McKendrick in epidemiology. At the University of Montana, we have developed a senior-level interdisciplinary course in Mathematical Biology, that serves the needs of our applied mathematics emphasis as well as the modelling needs of students in the Wildlife Biology and Chemistry programs. Many of the tools used in Mathematical Biology involve the analysis of nonlinear difference and differential equations (and systems). Although these topics may seem to be quite advanced for non-majors, most of these topics can be approached using graphical techniques easily mastered by upper-division students, even non-majors. Further, these tools provide genuine insight into the application of mathematics in the world around us. The models show how certain processes work in biology and predict outcomes that give insight into the biological mechanisms. Much of the course involves the use of eigenvalues in analyzing local behavior, a task also within the reach of interdisciplinary students. We discuss primarily 2-dimensional systems, but some mention is also made of behaviors in higher dimensions. A third aspect of the course is its use of technology: we use some simple TRUE BASIC programs to introduce certain models of population growth (Leslie model), and to discuss the chaotic behavior of logistic models. Students are then taught to use PHASE-PLANE, as a tool for finding numerical solutions of differential and discrete systems. This one-semester course includes aspects of chaotic motions, phase-plane analysis, and bifurcation theory, but virtually all of the theoretical material require only a basic understanding of sophomore calculus.